Mouse Monoclonal Antibody to CHK1

Item#:

sAP-0030

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0030
Product Name	Mouse Monoclonal Antibody to CHK1
Target Molecle	CHK1
Aliases	CHEK1
Species	Human, Mouse
MW	56kDa
Enterez GeneID	1111
General Information	CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.
Immunogen	Purified recombinant fragment of CHK1 expressed in E. Coli.
Clone	MM2G1D5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Clin Chem 1997,43 (7)