Mouse Monoclonal Antibody to Trim5a

Item#:

sAP-0023

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0023
Product Name	Mouse Monoclonal Antibody to Trim5a
Target Molecle	Trim5a
Aliases	RNF88; TRIM5alpha
Species	Human;
MW	N/A
Enterez GeneID	85364
General Information	TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.
Immunogen	Purified recombinant fragment of human trim5 alpha expressed in E. Coli.
Clone	MM3B11H2;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Sato Y,et.al. Journal of Gastroenterology,1996 Feb.31(1)