Mouse Monoclonal Antibody to IL-10

Item#:

sAP-0011

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0011
Product Name	Mouse Monoclonal Antibody to IL-10
Target Molecle	IL-10
Aliases	IL10
Species	Human
MW	N/A
Enterez GeneID	3586
General Information	Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Immunogen	Purified recombinant fragment of human IL-10 expressed in E. Coli.
Clone	MM3C12C12;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Du,Y.; et al. 2000. Neurology 55