Mouse Monoclonal Antibody to Nucleophosmin

Item#:

sAP-0001

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0001
Product Name	Mouse Monoclonal Antibody to Nucleophosmin
Target Molecle	Nucleophosmin
Aliases	B23; NPM
Species	Human; Monkey;
MW	33kDa
Enterez GeneID	4869
General Information	Nucleophosmin (NPM), also named B23 or NO38, is a major nucleolar protein which is 20 times more abundant in tumor or proliferating cells than in normal resting cells. NPM has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.
Immunogen	Purified recombinant fragment of human NPM (2-265) expressed in E. Coli.
Clone	MM7H10B9;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	References