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Goat anti-Cryopirin / NALP3 / NLRP3 Antibody
Item#:
dAP-3320
Size Price Quantity
50.0 ug $310.00
Goat anti-Cryopirin / NALP3 / NLRP3 Antibody
Principle Name Cryopirin / NALP3 / NLRP3
Official Symbol NLRP3
All Name and Symbols NLRP3; NLR family, pyrin domain containing 3; AGTAVPRL; AII; AII/AVP; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCU; FLJ95925; MWS; NALP3; PYPAF1; AII/AVP receptor-like; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; NACHT, LRR and PYD contain
Accession Number(s) NP_004886.3; NP_899632.1; NP_001120933.1; NP_001120934.1
Peptide Sequence NQERTSYLEKKLSCK, is from internal region
Human Gene ID(s) 114548
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize all reported isoforms (NP_004886.3; NP_899632.1; NP_001120933.1; NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA
Tested Species
Peptide ELISA antibody detection limit dilution 1 to 4000.
Western Blot Preliminary experiments in Human Bone Marrow and Peripheral Blood Lymphocytes lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any
Reference(s) Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, Brown GD, Fitzgerald KA, An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell host & microbe 2009 May 5 (5)

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