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Goat anti-HMBS (aa160-173) Antibody
Item#:
dAP-3284
Size Price Quantity
50.0 ug $310.00
Goat anti-HMBS (aa160-173) Antibody
Principle Name HMBS (aa160-173)
Official Symbol HMBS
All Name and Symbols HMBS; hydroxymethylbilane synthase; PBG-D; PBGD; PORC; UPS; porphobilinogen deaminase; porphyria, acute; Chester type; pre-uroporphyrinogen synthase; uroporphyrinogen I synthase; uroporphyrinogen I synthetase
Accession Number(s) NP_000181.2; NP_001019553.1; NP_001245137.1; NP_001245138.1
Peptide Sequence HLEFRSIRGNLNTR, is from internal region
Human Gene ID(s) 3145
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize all reported isoforms (NP_000181.2; NP_001019553.1; NP_001245137.1; NP_001245138.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 40kDa band observed in lysates of cell line K562 (calculated MW of 39.3kDa according to NP_000181.2). Recommended concentration
Reference(s) Brancaleoni V, Granata F, Colancecco A, Tavazzi D, Cappellini MD, Di Pierro E. Seven novel genetic mutations within the 5'UTR and the housekeeping promoter of HMBS gene responsible for the non-erythroid form of acute intermittent porphyria. Blood cells, molecules & diseases 49 (3-4)

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