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Goat anti-ORL1 / LOX1 / LOXIN Antibody
Item#:
dAP-3268
Size Price Quantity
50.0 ug $310.00
Goat anti-ORL1 / LOX1 / LOXIN Antibody
Principle Name ORL1 / LOX1 / LOXIN
Official Symbol OLR1
All Name and Symbols OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; CLEC8A; LOX1; LOXIN; SCARE1; SLOX1; C-type lectin domain family 8 member A; OTTHUMP00000238950; OTTHUMP00000238954; OTTHUMP00000238955; OTTHUMP00000238958; hLOX-1; lectin-type oxidized LDL r
Accession Number(s) NP_002534.1; NP_001166103.1; NP_001166104.1
Peptide Sequence DLKIQTVKDQPDEK, is from N Terminus
Human Gene ID(s) 4973
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize all reported isoforms (NP_002534.1; NP_001166103.1; NP_001166104.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 40kDa band observed in Human Liver lysates (calculated MW of 30.9kDa according to NP_002534.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Yoshida et al, Biochem J. 1998 Aug
Reference(s) Shi Y, Cosentino F, Camici GG, Akhmedov A, Vanhoutte PM, Tanner FC, Lüscher TF. Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. Arterioscler Thromb Vasc Biol. 2011 Sep;31(9)

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