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Goat anti-SCARB1 / SR-BI Antibody
Item#:
dAP-3144
Size Price Quantity
50.0 ug $310.00
Goat anti-SCARB1 / SR-BI Antibody
Principle Name SCARB1 / SR-BI
Official Symbol SCARB1
All Name and Symbols SCARB1; scavenger receptor class B, member 1; CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; scavenger receptor class B member 1; scavenger receptor class B
Accession Number(s) NP_005496.4
Peptide Sequence TSAPKGSVLQEAK, is from C Terminus
Human Gene ID(s) 949
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize isoform 1 (NP_005496.4) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 85kDa band observed in Human Adrenal gland lysates (calculated MW of 57.0kDa according to NP_005496.4). We do note that SCARB1 is a glycoprotein which makes a higher size band to be expected, and this is consistent with observations
Reference(s) Zhang QH, Zu XY, Cao RX, Liu JH, Mo ZC, Zeng Y, Li YB, Xiong SL, Liu X, Liao DF, Yi GH. An involvement of SR-B1 mediated PI3K-Akt-eNOS signaling in HDL-induced cyclooxygenase 2 expression and prostacyclin production in endothelial cells. Biochem Biophys Res Commun. 2012 Mar 30;420(1)

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