Goat anti-OAS1 Antibody |
Principle Name | OAS1 |
Official Symbol | OAS1 |
All Name and Symbols | OAS1; 2'-5'-oligoadenylate synthetase 1, 40/46kDa; IFI-4; OIAS; OIASI; (2-5')oligo(A) synthase 1; (2-5')oligo(A) synthetase 1; 2',5'-oligo A synthetase 1; 2',5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5' oligoadenylate synthetase 1 p48 isoform; 2'-5' ol |
Accession Number(s) | NP_058132.2 |
Peptide Sequence | THEYPHFSHRPST, is from internal region (near C terminus) |
Human Gene ID(s) | 4938 |
Non-Human GeneID(s) | |
Important Comments | This antibody is expected to recognize isoforms 1 (NP_058132.2) only. |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
Applications | Pep ELISA, WB |
Tested Species | Human |
Peptide ELISA | antibody detection limit dilution 1 to 128000. |
Western Blot | Approx 50kDa band observed in lysates of cell line HepG2 (calculated MW of 46.0kDa according to NP_058132.2). Recommended concentration |
Reference(s) | Li CZ, Kato N, Chang JH, Muroyama R, Shao RX, Dharel N, Sermsathanasawadi R, Kawabe T, Omata M. Polymorphism of OAS-1 determines liver fibrosis progression in hepatitis C by reduced ability to inhibit viral replication. Liver international |