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Goat anti-kininogen 1 Antibody
Item#:
dAP-2995
Size Price Quantity
50.0 ug $310.00
Goat anti-kininogen 1 Antibody
Principle Name kininogen 1
Official Symbol KNG1
All Name and Symbols KNG1; kininogen 1; BDK; KNG; HMWK; alpha-2-thiol proteinase inhibitor; bradykinin; fitzgerald factor; high molecular weight kininogen; kininogen-1; williams-Fitzgerald-Flaujeac factor
Accession Number(s) NP_001095886.1; NP_000884.1; NP_001159923.1
Peptide Sequence RITEATKTVGSDT, is from internal region (near N terminus)
Human Gene ID(s) 3827
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize all reported isoforms (NP_001095886.1; NP_000884.1; NP_001159923.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 80+60+30kDa bands observed in Human Kidney lysates (calculated MW of 72.0kDa according to NP_001095886.1). The observed MW bands are explained by glycosylation and the splitting into heavy and light chains from the precursor protein.
Reference(s) Kolte D, Osman N, Yang J, Shariat-Madar Z. High molecular weight kininogen activates B2 receptor signaling pathway in human vascular endothelial cells. J Biol Chem. 2011 Jul 15;286(28)

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