Goat anti-ERCC6 (aa717-731) Antibody

Item#:

dAP-2984

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-ERCC6 (aa717-731) Antibody
Principle Name	ERCC6 (aa717-731)
Official Symbol	ERCC6
All Name and Symbols	ERCC6; excision repair cross-complementing rodent repair deficiency, complementation group 6; ARMD5; CKN2; COFS; COFS1; CSB; RAD26; ATP-dependent helicase ERCC6; Cockayne syndrome B protein; Cockayne syndrome group B protein; DNA excision repair protein E
Accession Number(s)	NP_000115.1
Peptide Sequence	SNASPVQVKTAYKCA, is from internal region
Human Gene ID(s)	2074
Non-Human GeneID(s)	319955 (mouse); 306274 (rat);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 128000.
Western Blot	Approx 170kDa band observed in nuclear lysates of cell line HeLa (calculated MW of 168kDa according to NP_000115.1). Recommended concentration
Reference(s)	Zhang H, Gao J, Ye J, Gong Z, Gu X. Maternal origin of a de novo microdeletion spanning the ERCC6 gene in a classic form of the Cockayne syndrome. Eur J Med Genet. 2011 Jul-Aug;54(4)