Goat anti-BATF Antibody |
| Principle Name | BATF |
| Official Symbol | BATF |
| All Name and Symbols | BATF; basic leucine zipper transcription factor, ATF-like; B-ATF; BATF1; SFA-2; SFA2; B-cell-activating transcription factor; SF-HT-activated gene 2 protein; activating transcription factor B; basic leucine zipper transcriptional factor ATF-like |
| Accession Number(s) | NP_006390.1 |
| Peptide Sequence | EVVYSAHAFHQPHVS, is from C Terminus |
| Human Gene ID(s) | 10538 |
| Non-Human GeneID(s) | 53314 (mouse); 299206 (rat); |
| Important Comments | |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA |
| Tested Species | |
| Peptide ELISA | antibody detection limit dilution 1 to 128000. |
| Western Blot | Preliminary experiments gave an approx 25kDa band in Human Spleen lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 14.1kD |
| Reference(s) | Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, Crawford A, Shin H, Kwon DS, Zupkosky J, Francisco L, Freeman GJ, Wherry EJ, Kaufma Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nature medicine 2010 Oct 16 (10) |
