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Goat anti-p15INK4b (isoform 2) Antibody


Item#:
dAP-2919
Size Price Quantity
50.0 ug $310.00
Goat anti-p15INK4b (isoform 2) Antibody
Principle Name p15INK4b (isoform 2)
Official Symbol CDKN2B
All Name and Symbols CDKN2B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); CDK4I; INK4B; MTS2; P15; TP15; p15INK4b; CDK inhibitory protein; CDK4B inhibitor; MTS-2; cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinases 4 and 6 binding protein; multiple t
Accession Number(s) NP_004927.2; NP_511042.1
Peptide Sequence RQGARERGARP, is from C Terminus
Human Gene ID(s) 1030
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize isoform 2 (NP_511042.1) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 12+14kDa bands observed in Human Gastrointestinal cancer lysates (calculated MW of 8.1kDa according to NP_511042.1). The observed 14kDa cannot represent isoform 1 and therefore it most likely represents another posttranslational modi
Reference(s) Geyer CR. Strategies to re-express epigenetically silenced p15(INK4b) and p21(WAF1) genes in acute myeloid leukemia. Epigenetics. 2010 Nov-Dec;5(8)

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