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Goat anti-Glycine receptor, alpha 1 (intracellular) Antibody
Item#:
dAP-2773
Size Price Quantity
50.0 ug $310.00
Goat anti-Glycine receptor, alpha 1 (intracellular) Antibody
Principle Name Glycine receptor, alpha 1 (intracellular)
Official Symbol Glra1
All Name and Symbols Glra1; glycine receptor, alpha 1; GLYRA1; glycine receptor 48 kDa subunit; glycine receptor strychnine-binding subunit; glycine receptor subunit alpha-1; glycine receptor, alpha 1 subunit
Accession Number(s) NP_037265.1
Peptide Sequence CLQAKDGISVKGAN, is from internal region
Human Gene ID(s) 2741
Non-Human GeneID(s) 14654 (mouse); 25674 (rat);
Important Comments The immunizing peptide represents part of the cytoplasmic domain. The antibody is not expected to cross-react with other glycine receptor alpha proteins.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Mouse, Rat
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 60kDa band observed in Mouse and Rat Testis lysates (calculated MW of 51.7kDa according to Mouse NP_065238.2). The observed molecular weight corresponds to the glycosylated form. Recommended concentration
Reference(s) Wang Q, Lynch JW. Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor. J Biol Chem. 2011 Nov 4;286(44)

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