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Goat anti-DYRK1A Antibody
Item#:
dAP-2741
Size Price Quantity
50.0 ug $310.00
Goat anti-DYRK1A Antibody
Principle Name DYRK1A
Official Symbol DYRK1A
All Name and Symbols DYRK1A; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; DYRK; DYRK1; HP86; MNB; MNBH; MRD7; MNB/DYRK protein kinase; OTTHUMP00000109090; OTTHUMP00000109091; OTTHUMP00000109094; OTTHUMP00000174799; dual specificity YAK1-related kinase; d
Accession Number(s) NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1
Peptide Sequence PHSHQYSDRRQPN, is from N Terminus
Human Gene ID(s) 1859
Non-Human GeneID(s) 13548 (mouse); 25255 (rat);
Important Comments This antibody is expected to recognize all reported isoforms (NP_001387.2; NP_569120.1; NP_567824.1; NP_569122.1). This antibody is not expected to cross-react with DYRK1B.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 64000.
Western Blot Approx 80kDa band observed in lysates of cell line K562 (calculated MW of 85.6kDa according to NP_001387.2). Recommended concentration
Reference(s) Miyata Y, Nishida E. DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation. Biochim Biophys Acta. 2011 Oct;1813(10)

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