Goat anti-Uromodulin (aa525-536) Antibody

Item#:

dAP-2721

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-Uromodulin (aa525-536) Antibody
Principle Name	Uromodulin (aa525-536)
Official Symbol	UMOD
All Name and Symbols	UMOD; uromodulin; ADMCKD2; FJHN; HNFJ; HNFJ1; MCKD2; THGP; THP; OTTHUMP00000162212; OTTHUMP00000162213; Tamm-Horsfall glycoprotein; tamm-Horsfall urinary glycoprotein; uromodulin (uromucoid, Tamm-Horsfall glycoprotein); uromucoid
Accession Number(s)	NP_003352.2
Peptide Sequence	DRCPHTRDSTIQ, is from internal region
Human Gene ID(s)	7369
Non-Human GeneID(s)
Important Comments	Reported variants represent identical protein
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 128000.
Western Blot	Approx 80kDa band observed in lysates of cell line HeLa (calculated MW of 69.8kDa according to NP_003352.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Williams et al, Hum Mol Gene
Reference(s)	Ahluwalia TS, Lindholm E, Groop L, Melander O. Uromodulin gene variant is associated with type 2 diabetic nephropathy. J Hypertens. 2011 Sep;29(9)