Goat anti-Lamin B1 (isoform 1) Antibody

Item#:

dAP-2718

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-Lamin B1 (isoform 1) Antibody
Principle Name	Lamin B1 (isoform 1)
Official Symbol	LMNB1
All Name and Symbols	LMNB1; lamin B1; ADLD; LMN; LMN2; LMNB; MGC111419; OTTHUMP00000159218; lamin-B1
Accession Number(s)	NP_005564.1
Peptide Sequence	KESDLNGAQIKLRE, is from internal region
Human Gene ID(s)	4001
Non-Human GeneID(s)
Important Comments	This antibody is expected to recognize isoform 1 (NP_005564.1) only.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 128000.
Western Blot	Approx 65kDa band observed in lysates of cell line Jurkat (calculated MW of 66.4kDa according to NP_005564.1). Recommended concentration
Reference(s)	Schuster J, Sundblom J, Thuresson AC, Hassin-Baer S, Klopstock T, Dichgans M, Cohen OS, Raininko R, Melberg A, Dahl N. Genomic duplications mediate overexpression of lamin B1 in adult-onset autosomal dominant leukodystrophy (ADLD) with autonomic symptoms. Neurogenetics. 2011 Feb;12(1)