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Goat anti-Alpha-synuclein Antibody
Item#:
dAP-2709
Size Price Quantity
50.0 ug $310.00
Goat anti-Alpha-synuclein Antibody
Principle Name Alpha-synuclein
Official Symbol SNCA
All Name and Symbols SNCA; synuclein, alpha (non A4 component of amyloid precursor); NACP; PARK1; PARK4; PD1; alpha-synuclein; non A-beta component of AD amyloid; synuclein alpha-140
Accession Number(s) NP_009292.1; NP_000336.1
Peptide Sequence ATGFVKKDQLGK, is from internal region
Human Gene ID(s) 6622
Non-Human GeneID(s) 20617 (mouse); 29219 (rat);
Important Comments This antibody is expected to recognize both reported isoforms (NP_009292.1; NP_000336.1). Reported variants represent identical protein
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human, Mouse
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 17kDa band observed in Human Brain (Amygdala) and fetal Mouse Brain lysates (calculated MW of 14.5kDa according to Human NP_000336.1 and Mouse NP_033247.1). The observed molecular weight corresponds to earlier findings with different
Reference(s) Oueslati A, Paleologou KE, Schneider BL, Aebischer P, Lashuel HA. Mimicking phosphorylation at serine 87 inhibits the aggregation of human a-synuclein and protects against its toxicity in a rat model of Parkinson's disease. J Neurosci. 2012 Feb 1;32(5)

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