Goat anti-PDE4B Antibody |
| Principle Name | PDE4B |
| Official Symbol | PDE4B |
| All Name and Symbols | PDE4B; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); DPDE4; PDEIVB; Phosphodiesterase-4B, cAMP-specific (dunce (Drosophila)-homolog; phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase |
| Accession Number(s) | NP_002591.2; NP_001032416.1; NP_001032417.1 |
| Peptide Sequence | IDIATEDKSPVDT, is from C Terminus |
| Human Gene ID(s) | 5142 |
| Non-Human GeneID(s) | 18578 (mouse); |
| Important Comments | This antibody is expected to recognize all reported isoforms (NP_002591.2; NP_001032416.1; NP_001032417.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 98kDa band observed in Human Uterus lysates (calculated MW of 83.3kDa according to NP_002591.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Méhats et al, Endocrinology. 1999 |
| Reference(s) | Kim SW, Rai D, Aguiar RC. Gene set enrichment analysis unveils the mechanism for the phosphodiesterase 4B control of glucocorticoid response in B-cell lymphoma. Clin Cancer Res. 2011 Nov 1;17(21) |
