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Goat anti-Progranulin aa248-259 / Granulin-3 Antibody
Item#:
dAP-2593
Size Price Quantity
50.0 ug $310.00
Goat anti-Progranulin aa248-259 / Granulin-3 Antibody
Principle Name Progranulin aa248-259 / Granulin-3
Official Symbol GRN
All Name and Symbols GRN; granulin; GEP; GP88; PCDGF; PEPI; PGRN; PC cell-derived growth factor; acrogranin; granulin-epithelin; granulins; proepithelin; progranulin
Accession Number(s) NP_002078.1
Peptide Sequence PQDTVCDLIQSK, is from internal
Human Gene ID(s) 2896
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize the C-Terminal part of Granulin-3.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pept ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 8000.
Western Blot Approx 75kDa band observed in lysates of cell lines A431, A549 and HeLa (calculated MW of 63.5kDa according to NP_002078.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (He and Bat
Reference(s) Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C, Haass C. Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. J Neurosci. 2011 Feb 2;31(5)

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