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Goat anti-cytochrome P450 2C8 Antibody
Item#:
dAP-2522
Size Price Quantity
50.0 ug $310.00
Goat anti-cytochrome P450 2C8 Antibody
Principle Name cytochrome P450 2C8
Official Symbol CYP2C8
All Name and Symbols CYP2C8; cytochrome P450, family 2, subfamily C, polypeptide 8; CPC8; CYPIIC8; MP-12/MP-20; P450 form 1; cytochrome P450 2C8; cytochrome P450 IIC2; cytochrome P450 MP-12; cytochrome P450 MP-20; cytochrome P450 form 1; cytochrome P450, subfamily IIC (mephen
Accession Number(s) NP_000761.3; NP_001185782.1; NP_001185783.1
Peptide Sequence KNVALTRSYIREK, is from internal region
Human Gene ID(s) 1558
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize all reported isoforms (NP_000761.3; NP_001185782.1; NP_001185783.1). No cross-reactivity with other 2C proteins expected. Reported variants represent identical protein
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 55kDa band observed in Human Liver lysates (calculated MW of 55.8kDa according to NP_000761.3). Recommended concentration
Reference(s) Leskelä S, Jara C, Leandro-García LJ, Martínez A, García-Donas J, Hernando S, Hurtado A, Vicario JC, Montero-Conde C, Landa I, López-Jiménez E, Cascón A, Milne RL, Robledo M, Rodríguez-Antona C. Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity. Pharmacogenomics J. 2011 Apr;11(2)

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