Goat anti-FGFR1 Antibody |
| Principle Name | FGFR1 |
| Official Symbol | FGFR1 |
| All Name and Symbols | FGFR1; fibroblast growth factor receptor 1; BFGFR; CD331; CEK; FGFBR; FLG; FLJ99988; FLT2; HBGFR; KAL2; N-SAM; OGD; FGFR-1; FLT-2; FMS-like tyrosine kinase 2; OTTHUMP00000190875; OTTHUMP00000190876; OTTHUMP00000190880; bFGF-R-1; basic fibroblast growth fa |
| Accession Number(s) | NP_075598.2; NP_056934.2; NP_075593.1; NP_075594.1; NP_001167534.1; NP_001167535.1; NP_001167538.1 |
| Peptide Sequence | RCRLRDDVQSIN, is from internal region |
| Human Gene ID(s) | 2260 |
| Non-Human GeneID(s) | 14182 (mouse); 79114 (rat); |
| Important Comments | This antibody is expected to recognize reported isoforms 1, 2, 10, 11 and 14. Reported variants represent identical protein |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 8000. |
| Western Blot | Approx 85kDa band observed in lysates of cell line A549 (calculated MW of 91.9kDa according to NP_075598.2). Recommended concentration |
| Reference(s) | Weiss J, et al Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med. 2010 Dec 15;2(62) |
