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Goat anti-MKRN1 (aa105-118) Antibody
Item#:
dAP-2479
Size Price Quantity
50.0 ug $310.00
Goat anti-MKRN1 (aa105-118) Antibody
Principle Name MKRN1 (aa105-118)
Official Symbol MKRN1
All Name and Symbols MKRN1; makorin ring finger protein 1; FLJ21334; RNF61; E3 ubiquitin-protein ligase makorin-1; OTTHUMP00000212121; OTTHUMP00000212124; RING finger protein 61
Accession Number(s) NP_038474.2; NP_001138597.1
Peptide Sequence RYEHSKPLKQEEAT, is from internet regoin
Human Gene ID(s) 23608
Non-Human GeneID(s) 54484 (mouse);
Important Comments This antibody is expected to recognize both reported isoforms (NP_038474.2; NP_001138597.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human, Mouse
Peptide ELISA antibody detection limit dilution 1 to 64000.
Western Blot Approx 50kDa band observed in fetal Mouse Brain lysates and 35kDa plus fainter 50kDa bands in adult Mouse Brain lysates (calculated MW of 52.9kDa according to NP_061280.2). The observed 35kDa band corresponds to the calculated MW of human i
Reference(s) Kim JH, Park SM, Kang MR, Oh SY, Lee TH, Muller MT, Chung IK. Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev. 2005 Apr 1;19(7)

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