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Goat anti-TSHR (aa101-115) Antibody
Item#:
dAP-2469
Size Price Quantity
50.0 ug $310.00
Goat anti-TSHR (aa101-115) Antibody
Principle Name TSHR (aa101-115)
Official Symbol TSHR
All Name and Symbols TSHR; thyroid stimulating hormone receptor; CHNG1; LGR3; MGC75129; hTSHR-I; TSH-R; seven transmembrane helix receptor; thyroid-stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I
Accession Number(s) NP_000360.2; NP_001018046.1
Peptide Sequence SKVTHIEIRNTRNLT, is from internal region
Human Gene ID(s) 7253
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 16000.
Western Blot Approx 28kDa band observed in Human Thyroid Gland lysates (calculated MW of 28.4kDa according to NP_001018046.1). Recommended concentration
Reference(s) Nishihara E, Chen CR, Higashiyama T, Mizutori-Sasai Y, Ito M, Kubota S, Amino N, Miyauchi A, Rapoport B. Subclinical nonautoimmune hyperthyroidism in a family segregates with a thyrotropin receptor mutation with weakly increased constitutive activity. Thyroid. 2010 Nov;20(11)

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