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Goat anti-TGFBR1 (aa50-63) Antibody
Item#:
dAP-2460
Size Price Quantity
50.0 ug $310.00
Goat anti-TGFBR1 (aa50-63) Antibody
Principle Name TGFBR1 (aa50-63)
Official Symbol TGFBR1
All Name and Symbols TGFBR1; transforming growth factor, beta receptor 1; AAT5; ACVRLK4; ALK-5; ALK5; LDS1A; LDS2A; SKR4; TGFR-1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; activin A receptor type II-like kinase, 53kD; activin A receptor typ
Accession Number(s) NP_004603.1; NP_001124388.1
Peptide Sequence TDGLCFVSVTETTD, is from internal region
Human Gene ID(s) 7046
Non-Human GeneID(s) 21812 (mouse); 29591 (rat);
Important Comments This antibody is expected to recognize both reported isoforms (NP_004603.1; NP_001124388.1). The immunizing peptide represents part of a potential extracellular domain.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Rat, Human
Peptide ELISA antibody detection limit dilution 1 to 64000.
Western Blot Approx 55kDa band observed in Rat Liver lysates (calculated MW of 55.6kDa according to Rat NP_036907.2). Recommended concentration
Immunohistochemistry Paraffin embedded Human Adrenal Gland. Recommended concentration
Reference(s) Yu N, Kozlowski JM, Park II, Chen L, Zhang Q, Xu D, Doll JA, Crawford SE, Brendler CB, Lee C. Overexpression of transforming growth factor ß1 in malignant prostate cells is partly caused by a runaway of TGF-ß1 auto induction mediated through a defective recruitment of protein phosphatase 2A by TGF-ß type I receptor. Urology. 2010 Dec;76(6)

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