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Goat anti-Tph2 (mouse) Antibody
Item#:
dAP-2454
Size Price Quantity
50.0 ug $310.00
Goat anti-Tph2 (mouse) Antibody
Principle Name Tph2 (mouse)
Official Symbol Tph2
All Name and Symbols Tph2; tryptophan hydroxylase 2; AU043594; MGC159133; Ntph; OTTMUSP00000022885; neuronal tryptophan hydroxylase; tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2
Accession Number(s) NP_775567.2
Peptide Sequence SLTQNKAIKSEDK, is from internal region
Human Gene ID(s)
Non-Human GeneID(s) 216343 (mouse);
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, IHC
Tested Species Mouse
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Preliminary experiments gave an approx 85kDa band in Mouse fetal Brain lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of
Immunohistochemistry In paraffin embedded Mouse Brain stem shows staining of Raphe nucleii serotonergic neurons consistent with observation by different antibodies. Recommended concentration, 0.5-2µg/ml.
Reference(s) Zhou Z, Roy A, Lipsky R, Kuchipudi K, Zhu G, Taubman J, Enoch MA, Virkkunen M, Goldman D. Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations. Arch Gen Psychiatry. 2005 Oct;62(10)

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