Goat anti-ATXN1 (aa686-699) Antibody

Item#:

dAP-2408

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-ATXN1 (aa686-699) Antibody
Principle Name	ATXN1 (aa686-699)
Official Symbol	ATXN1
All Name and Symbols	ATXN1; ataxin 1; ATX1; D6S504E; SCA1; OTTHUMP00000016065; ataxin-1; spinocerebellar ataxia type 1 protein
Accession Number(s)	NP_000323.2
Peptide Sequence	TLKNLKNGSVKKGQ, is from internal region
Human Gene ID(s)	6310
Non-Human GeneID(s)	20238 (mouse); 25049 (rat);
Important Comments	Reported variants represent identical protein
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA
Tested Species
Peptide ELISA	antibody detection limit dilution 1 to 32000.
Western Blot	Preliminary experiments gave bands at approx 75kDa and 26kDa in Mouse Fetal Brain lysates after 0.5µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calcul
Reference(s)	Duvick L, Barnes J, Ebner B, Agrawal S, Andresen M, Lim J, Giesler GJ, Zoghbi HY, Orr HT, SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776. Neuron 2010 Sep 67 (6)