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Goat anti-MTHFD1L (aa535-538) Antibody
Item#:
dAP-2382
Size Price Quantity
50.0 ug $310.00
Goat anti-MTHFD1L (aa535-538) Antibody
Principle Name MTHFD1L (aa535-538)
Official Symbol MTHFD1L
All Name and Symbols MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; DKFZp586G1517; FLJ21145; FTHFSDC1; MTC1THFS; dJ292B18.2; 10-formyl-THF synthetase; formyltetrahydrofolate synthetase domain containing 1; mitochondrial C1-tetrahydrofolate synthase
Accession Number(s) NP_056255.2
Peptide Sequence DTNDRFLRKITIGQ, is from internal region
Human Gene ID(s) 25902
Non-Human GeneID(s) 270685 (mouse); 361472 (rat);
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human, Mouse, Rat
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Approx 110kDa band observed in Human Brain (Cerebellum) (calculated MW of 106kDa according to NP_056255.2). The same band is observed in lysates of cell line NIH3T3, Mouse Brain and Rat Brain. Recommended concentration
Immunohistochemistry Paraffin embedded Human Kidney. Recommended concentration
Reference(s) Parle-McDermott A, Pangilinan F, O'Brien KK, Mills JL, Magee AM, Troendle J, Sutton M, Scott JM, Kirke PN, Molloy AM, Brody LC, A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency. Human mutation 2009 Dec 30 (12)

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