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Goat anti-Scn10a / Nav1.8 (mouse) Antibody


Item#:
dAP-2363
Size Price Quantity
50.0 ug $310.00
Goat anti-Scn10a / Nav1.8 (mouse) Antibody
Principle Name Scn10a / Nav1.8 (mouse)
Official Symbol Scn10a
All Name and Symbols Scn10a; sodium channel, voltage-gated, type X, alpha subunit; Nav1.8; PN3; SNS; mPN3; peripheral nerve sodium channel 3; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel, voltage-gated, type X, alph
Accession Number(s) NP_033160.2
Peptide Sequence DDNRSLQSDPYNQR, is from internal region
Human Gene ID(s) 6336
Non-Human GeneID(s) 20264 (mouse); 29571 (rat);
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA
Tested Species
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot Preliminary experiments gave an approx 150kDa band in Rat Spinal Cord and NIH3T3 lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated
Reference(s) Li Q, Su YY, Wang H, Li L, Wang Q, Bao L, Transmembrane segments prevent surface expression of sodium channel Nav1.8 and promote calnexin-dependent channel degradation. The Journal of biological chemistry 2010 Oct 285 (43)

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