Goat anti-Plakophilin 2 (aa125-139) Antibody

Item#:

dAP-2350

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-Plakophilin 2 (aa125-139) Antibody
Principle Name	Plakophilin 2 (aa125-139)
Official Symbol	PKP2
All Name and Symbols	PKP2; plakophilin 2; ARVD9; MGC177501; plakophilin-2
Accession Number(s)	NP_001005242.2; NP_004563.2
Peptide Sequence	RGTAQYSSQKSVEER, is from internal region
Human Gene ID(s)	5318
Non-Human GeneID(s)	67451 (mouse); 287925 (rat);
Important Comments	This antibody is expected to recognize both reported isoforms (NP_001005242.2; NP_004563.2).
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Mouse, Rat
Peptide ELISA	antibody detection limit dilution 1 to 16000.
Western Blot	Approx 100kDa band observed in Mouse and Rat Heart lysates (calculated MW of 88.1kDa according to Mouse NP_080439.1 and 87.8kDa according to Rat NP_001093969.1). Recommended concentration
Reference(s)	Christensen AH, Benn M, Tybjaerg-Hansen A, Haunso S, Svendsen JH, Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders? Cardiology 2010 115 (2)