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Goat anti-GM2A (aa 179-189) Antibody
Item#:
dAP-2333
Size Price Quantity
50.0 ug $310.00
Goat anti-GM2A (aa 179-189) Antibody
Principle Name GM2A (aa 179-189)
Official Symbol GM2A
All Name and Symbols GM2A; GM2 ganglioside activator; SAP-3; cerebroside sulfate activator protein; sphingolipid activator protein 3
Accession Number(s) NP_000396.2
Peptide Sequence KRLGCIKIAAS, is from internal region
Human Gene ID(s) 2760
Non-Human GeneID(s) 14667 (mouse); 282838 (rat);
Important Comments This antibody is expected to recognize isoform 1 (NP_000396.2) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human, Rat
Peptide ELISA antibody detection limit dilution 1 to 4000.
Western Blot In transfected HEK293 transiently expressing full-length Human GM2A (myc and DYKDDDDK tagged), a band of approx. 28kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag an
Reference(s) Todeschini AR, Dos Santos JN, Handa K, Hakomori SI, Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse. The Journal of biological chemistry 2007 Mar 282 (11)

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