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Goat anti-PCSK9 (aa164-175) Antibody
Item#:
dAP-2282
Size Price Quantity
50.0 ug $310.00
Goat anti-PCSK9 (aa164-175) Antibody
Principle Name PCSK9 (aa164-175)
Official Symbol PCSK9
All Name and Symbols PCSK9; proprotein convertase subtilisin/kexin type 9 ; FH3; HCHOLA3; NARC-1; NARC1 ; hypercholesterolemia, autosomal dominant 3; neural apoptosis regulated convertase 1
Accession Number(s) NP_777596.2
Peptide Sequence PRYRADEYQPPD, is from internal region
Human Gene ID(s) 255738
Non-Human GeneID(s)
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB Trf
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 32000.
Western Blot In transfected HEK293 transiently expressing full-length Human PCSK9 (myc and DYKDDDDK tagged), a doublet of approx. 80-100kDa was observed. No bands were observed in mock-transfected HEK293 and the same bands were observed using anti-myc t
Reference(s) Lalanne F, Lambert G, Amar MJ, Chetiveaux M, Zair Y, Jarnoux AL, Ouguerram K, Friburg J, Seidah NG, Brewer HB Jr, Krempf M, Costet P. Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells. J Lipid Res. 2005 Jun;46(6)

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