Goat anti-MPV17 Antibody |
| Principle Name | MPV17 |
| Official Symbol | MPV17 |
| All Name and Symbols | MPV17; MpV17 mitochondrial inner membrane protein; SYM1; Mpv17 protein; Mpv17, human homolog of glomerulosclerosis and nephrotic syndrome; OTTHUMP00000122591 |
| Accession Number(s) | NP_002428.1 |
| Peptide Sequence | QRALAAHPWKVQ, is from internal region |
| Human Gene ID(s) | 4358 |
| Non-Human GeneID(s) | 17527 (mouse); 360463 (rat); |
| Important Comments | |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 19kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 19.7kDa according to NP_002428.1). Recommended concentration |
| Immunohistochemistry | In paraffin embedded Human Liver shows heavy textured cystoplasm staining in hepatocytes, consistent with mitochondia.. Recommended concentration, 5-10µg/ml. |
| Reference(s) | El-Hattab AW, Li FY, Schmitt E, Zhang S, Craigen WJ, Wong LJ, MPV17-associated hepatocerebral mitochondrial DNA depletion syndrome |
