Goat anti-FANCL Antibody |
| Principle Name | FANCL |
| Official Symbol | FANCL |
| All Name and Symbols | FANCL; Fanconi anemia, complementation group L; FAAP43; FLJ10335; PHF9; POG; PHD finger protein 9 |
| Accession Number(s) | NP_001108108.1; NP_060532.2 |
| Peptide Sequence | QNLKDVLEIDFP, is from internal region |
| Human Gene ID(s) | 55120 |
| Non-Human GeneID(s) | 67030 (mouse); 305600 (rat); |
| Important Comments | This antibody is expected to recognize both isoforms (NP_001108108.1; NP_060532.2). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 16000. |
| Western Blot | Approx 45kDa band observed in Human Bone Marrow lysates (calculated MW of 43.4kDa according to NP_001108108.1). Recommended concentration |
| Reference(s) | García MJ, Fernández V, Osorio A, Barroso A, Fernández F, Urioste M, Benítez J. Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition. Carcinogenesis 2009 Nov 30 (11) |
