Goat anti-ADAMTS8 Antibody

Item#:

dAP-2049

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-ADAMTS8 Antibody
Principle Name	ADAMTS8
Official Symbol	ADAMTS8
All Name and Symbols	ADAMTS8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; ADAM-TS8; FLJ41712; METH2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
Accession Number(s)	NP_008968.4
Peptide Sequence	QSSKERATTN, is from internal region
Human Gene ID(s)	11095
Non-Human GeneID(s)	30806 (mouse);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA
Tested Species
Peptide ELISA	antibody detection limit dilution 1 to 32000.
Western Blot	Preliminary experiments in Human Brain (Cerebellum), Lung and Placenta lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results
Reference(s)	Wågsäter D, Björk H, Zhu C, Björkegren J, Valen G, Hamsten A, Eriksson P. ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques. Atherosclerosis 2008 Feb 196 (2)