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Goat anti-CHRNA7 Antibody
Item#:
dAP-2005
Size Price Quantity
50.0 ug $310.00
Goat anti-CHRNA7 Antibody
Principle Name CHRNA7
Official Symbol CHRNA7
All Name and Symbols CHRNA7; cholinergic receptor, nicotinic, alpha 7; NACHRA7; a7 nicotinic acetylcholine receptor; alpha 7 neuronal nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; alpha7 nicotinic receptor subunit; cholinergic receptor, nic
Accession Number(s) NP_000737.1
Peptide Sequence KRPGEDKVRPACQHKQ, is from internal region
Human Gene ID(s) 1139
Non-Human GeneID(s) 11441 (mouse); 25302 (rat);
Important Comments This antibody also reacts with CHRNA7-FAM7A fusion isoform 1 (NP_647536.1) and isoform 2 (NP_683709.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, IHC
Tested Species Rat
Peptide ELISA antibody detection limit dilution 1 to 128000.
Immunohistochemistry In paraffin embedded Rat Cerebral Cortex and Rat Hippocampus shows membranous staining in neural cells. Recommended concentration, 5-10µg/ml.
Reference(s) Ren K, King MA, Liu J, Siemann J, Altman M, Meyers C, Hughes JA, Meyer EM The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice Neuroscience. 2007 Aug 10;148(1)

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