Goat anti-ADAMTSL2 Antibody

Item#:

dAP-1881

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-ADAMTSL2 Antibody
Principle Name	ADAMTSL2
Official Symbol	ADAMTSL2
All Name and Symbols	ADAMTSL2; ADAMTS-like 2; FLJ45164; KIAA0605; OTTHUMP00000064620; OTTHUMP00000162492
Accession Number(s)	NP_055509.2
Peptide Sequence	CTHVTGNYRKGNAH, is from internal region
Human Gene ID(s)	9719
Non-Human GeneID(s)	77794 (mouse); 311827 (rat);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA
Tested Species
Peptide ELISA	antibody detection limit dilution 1 to 128000.
Western Blot	Preliminary experiments gave an approx 25kDa band in Human Kidney, Liver and Lung lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calcula
Reference(s)	Le Goff C, Morice-Picard F, Dagoneau N, Wang LW, Perrot C, Crow YJ, Bauer F, Flori E, Prost-Squarcioni C, Krakow D, Ge G, Greenspan DS, Bonnet D, Le Merrer M, Munnich A, Apte SS, Cormier-Daire V, ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation. Nat Genet. 2008 Sep;40(9)