Goat anti-URP2 / kindlin-3 Antibody

Item#:

dAP-1872

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-URP2 / kindlin-3 Antibody
Principle Name	URP2 / kindlin-3
Official Symbol	FERMT3
All Name and Symbols	FERMT3; fermitin family homolog 3 (Drosophila); KIND3; MGC10966; MIG-2; MIG2B; UNC112C; URP2; URP2SF; UNC-112 related protein 2; fermitin family homolog 3; kindlin 3; kindlin-3
Accession Number(s)	NP_113659.3; NP_848537.1
Peptide Sequence	ERARGEELDED, is from C Terminus
Human Gene ID(s)	83706
Non-Human GeneID(s)	108101 (mouse); 309186 (rat);
Important Comments	This antibody is expected to recognize both isoforms (NP_113659.3, NP_848537.1).
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 2000.
Western Blot	Approx 75kDa band observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 75.4kDa according to NP_113659.3). Recommended concentration
Reference(s)	Svensson L, Howarth K, McDowall A, Patzak I, Evans R, Ussar S, Moser M, Metin A, Fried M, Tomlinson I, Hogg N. Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation. Nature medicine 2009 Mar 15 (3)