Goat anti-GGCX Antibody |
| Principle Name | GGCX |
| Official Symbol | GGCX |
| All Name and Symbols | GGCX; gamma-glutamyl carboxylase; FLJ26629; VKCFD1; vitamin K-dependent gamma-carboxylase |
| Accession Number(s) | NP_000812.2; NP_001135741.1 |
| Peptide Sequence | PPESNPDPVHSE, is from C Terminus |
| Human Gene ID(s) | 2677 |
| Non-Human GeneID(s) | |
| Important Comments | This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 85kDa band observed in Human Muscle lysates (calculated MW of 85kDa according to NP_000812.2). Recommended concentration |
| Immunohistochemistry | In paraffin embedded Human Kidney shows distinct staining in the cytoplasm of epthelial cells. Recommended concentration, 5-10µg/ml. |
| Reference(s) | Li Q, Grange DK, Armstrong NL, Whelan AJ, Hurley MY, Rishavy MA, Hallgren KW, Berkner KL, Schurgers LJ, Jiang Q, Uitto J, Mutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes. J Invest Dermatol. 2009 Mar;129(3) |
