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Goat anti-P2RX7 / P2X7 receptor Antibody


Item#:
dAP-1859
Size Price Quantity
50.0 ug $310.00
Goat anti-P2RX7 / P2X7 receptor Antibody
Principle Name P2RX7 / P2X7 receptor
Official Symbol P2RX7
All Name and Symbols P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; MGC20089; P2X7; ATP receptor; P2X purinoceptor 7; P2X7 receptor; P2Z receptor; purinergic receptor P2X7
Accession Number(s) NP_002553.2
Peptide Sequence YETNKVTRIQSMNY, is from N Terminus
Human Gene ID(s) 5027
Non-Human GeneID(s) 18439 (mouse); 29665 (rat);
Important Comments
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 16000.
Western Blot Approx 37kDa and 70kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 68.6kDa according to NP_002553.2). Recommended concentration
Immunohistochemistry In paraffin embedded Human Brain Cortex shows membranous staining of cell bodies and processes. Recommended concentration
Reference(s) Tomasinsig L, Pizzirani C, Skerlavaj B, Pellegatti P, Gulinelli S, Tossi A, Virgilio FD, Zanetti M, The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. The Journal of biological chemistry 2008 Nov 283 (45)

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