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Goat anti-CD11A / integrin alpha L Antibody
Item#:
dAP-1838
Size Price Quantity
50.0 ug $310.00
Goat anti-CD11A / integrin alpha L Antibody
Principle Name CD11A / integrin alpha L
Official Symbol ITGAL
All Name and Symbols ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; LFA-1; LFA1A; LFA-1 alpha; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; integrin alpha L; integrin g
Accession Number(s) NP_002200.2; NP_001107852.1
Peptide Sequence YQVRIQPSIHDHN, is from internal region
Human Gene ID(s) 3683
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize both reported isoforms (NP_002200.2; NP_001107852.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 16000.
Western Blot Approx 200kDa band observed in Human Spleen and Tonsil lysates (calculated MW of 129kDa according to NP_002200.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recomm
Immunohistochemistry In paraffin embedded Human Lymph Node shows membrane staining in the paracortex. Recommended concentration
Reference(s) Stanley P, Smith A, McDowall A, Nicol A, Zicha D, Hogg N, Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell. The EMBO journal 2008 Jan 27 (1)

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