Goat anti-HTR7 / 5-HT7 Antibody

Item#:

dAP-1799

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-HTR7 / 5-HT7 Antibody
Principle Name	HTR7 / 5-HT7
Official Symbol	HTR7
All Name and Symbols	HTR7; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-HT7; 5-hydroxytryptamine receptor 7; OTTHUMP00000020077; OTTHUMP00000020078; OTTHUMP00000020079; serotonin 5-HT-7 receptor
Accession Number(s)	NP_000863.1
Peptide Sequence	QNADYCRKKGHDS, is from C Terminus
Human Gene ID(s)	3363
Non-Human GeneID(s)
Important Comments	This antibody is expected to recognize isoform a (NP_000863.1) only.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 16000.
Western Blot	Approx 50kDa band observed in lysates of cell line KELLY (calculated MW of 49.5kDa according to NP_000863.1). Recommended concentration
Reference(s)	Sjögren B, Svenningsson P. Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a) receptors in HeLa cells. Acta physiologica (Oxford, England) 2007 May 190 (1)