Goat anti-KCNQ1 Antibody |
| Principle Name | KCNQ1 |
| Official Symbol | KCNQ1 |
| All Name and Symbols | KCNQ1; potassium voltage-gated channel, KQT-like subfamily, member 1; ATFB1; FLJ26167; JLNS1; KCNA8; KCNA9; KVLQT1; Kv1.9; Kv7.1; LQT; LQT1; RWS; SQT2; WRS; Jervell and Lange-Nielsen syndrome 1; kidney and cardiac voltage dependend K+ channel; long (elect |
| Accession Number(s) | NP_000209.2; NP_861463.1 |
| Peptide Sequence | EQLTVPRRGPDEGS, is from C Terminus |
| Human Gene ID(s) | 3784 |
| Non-Human GeneID(s) | 16535 (mouse); 84020 (rat); |
| Important Comments | This antibody is expected to recognize both reported isoforms (NP_000209.2; NP_861463.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 16000. |
| Western Blot | Approx. 60kDa band observed in Human Heart lysates (calculated MW of 61.5kDa according to NP_861463.1). Recommended concentration |
| Reference(s) | Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Ch Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet. 2008 Aug 17. [Epub ahead of print]..PMID |
