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Goat anti-Laforin (isoform a) Antibody
Item#:
dAP-1704
Size Price Quantity
50.0 ug $310.00
Goat anti-Laforin (isoform a) Antibody
Principle Name Laforin (isoform a)
Official Symbol EPM2A
All Name and Symbols epilepsy, progressive myoclonus type 2, Lafora disease (laforin); laforin; EPM2A; epilepsy, progressive myoclonus type 2A, Lafora disease (laforin); EPM2; MELF
Accession Number(s) NP_005661.1
Peptide Sequence EATGHTNEMKHTTD, is from internal region
Human Gene ID(s) 7957
Non-Human GeneID(s) 13853 (mouse); 680683 (rat);
Important Comments This antibody is expected to recognize isoform a (NP_005661.1) only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 16000.
Western Blot Approx. 38kDa band observed in Human Brain (Cerebellum), Mouse Brain and Rat Brain lysates (calculated MW of 37.2kDa according to NP_005661.1). Recommended concentration
Immunohistochemistry In paraffin embedded Human Cerebellum shows pixulate staining in the cells of the granular layer. Recommended concentration, 2.5-3.8µg/ml.
Reference(s) Mittal S, Dubey D, Yamakawa K, Ganesh S. Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment. Hum Mol Genet. 2007 Apr 1;16(7)

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