Goat anti-ADAM23 Antibody

Item#:

dAP-1694

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-ADAM23 Antibody
Principle Name	ADAM23
Official Symbol	ADAM23
All Name and Symbols	ADAM23 ; ADAM metallopeptidase domain 23 ; MDC3; a disintegrin and metalloproteinase domain 23
Accession Number(s)	NP_003803.1
Peptide Sequence	NGKPQYSKGGEHC, is from internal region
Human Gene ID(s)	8745
Non-Human GeneID(s)
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA
Tested Species
Peptide ELISA	antibody detection limit dilution 1 to 32000.
Western Blot	Preliminary experiments gave an approx 70kDa band in Human Brain (Cerebellum and Frontal Cortex) lysates after 0.7µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe. T
Reference(s)	Takada H, Imoto I, Tsuda H, Nakanishi Y, Ichikura T, Mochizuki H, Mitsufuji S, Hosoda F, Hirohashi S, Ohki M, Inazawa J. ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation. Oncogene. 2005 Dec 1;24(54)