Goat anti-TDP-43 Antibody

Item#:

dAP-1656

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-TDP-43 Antibody
Principle Name	TDP-43
Official Symbol	TARDBP
All Name and Symbols	TARDBP; TAR DNA binding protein; ALS10; TDP-43; OTTHUMP00000002171; TAR DNA-binding protein-43
Accession Number(s)	NP_031401.1
Peptide Sequence	HISNAEPKHNSNRQ, is from internal region
Human Gene ID(s)	23435
Non-Human GeneID(s)	230908 (mouse);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 16000.
Western Blot	Approx. 45kDa band observed in lysates of cell lines Jurkat (calculated MW of 44.7kDa according to NP_031401.1). A slightly larger protein is detected in some regions of the Brain. Recommended concentration
Reference(s)	Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, Bailey R, Pickering-Brown S, Dickson D, Petrucelli L. Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J. Neurosci. 2007 Sep 27 (39)