Goat anti-MTHFD1 Antibody

Item#:

dAP-1649

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-MTHFD1 Antibody
Principle Name	MTHFD1
Official Symbol	MTHFD1
All Name and Symbols	MTHFD1 ; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase ; MTHFC; MTHFD; 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 1
Accession Number(s)	NP_005947.2
Peptide Sequence	RGDLNDCFIPCTPK, is from internal region
Human Gene ID(s)	4522
Non-Human GeneID(s)	108156 (mouse); 64300 (rat);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 1000.
Western Blot	Approx. 110kDa band observed in Human Brain (substantia nigra) lysates (calculated MW of 102kDa according to NP_005947.2). Recommended concentration
Reference(s)	Dorszewska J, Florczak J, Rozycka A, Kempisty B, Jaroszewska-Kolecka J, Chojnacka K, Trzeciak WH, Kozubski W. Oxidative DNA damage and level of thiols as related to polymorphisms of MTHFR, MTR, MTHFD1 in Alzheimer's and Parkinson's diseases. Acta Neurobiol Exp (Wars). 2007;67(2)