Home Page > ANTIBODY > POLYCLONAL ANTIBODY > Goat Polyclonal Antibodies >  Goat anti-PMSCL1 Antibody

Goat anti-PMSCL1 Antibody
Item#:
dAP-1618
Size Price Quantity
50.0 ug $310.00
Goat anti-PMSCL1 Antibody
Principle Name PMSCL1
Official Symbol EXOSC9
All Name and Symbols EXOSC9; exosome component 9; PM/Scl-75; PMSCL1; RRP45; Rrp45p; p5; p6; P75 polymyositis-scleroderma overlap syndrome associated autoantigen; PMSCL autoantigen, 75kD; autoantigen PM/Scl 1; polymyositis/scleroderma autoantigen 1 (75kD); polymyositis/sclerod
Accession Number(s) NP_001029366.1; NP_005024.2
Peptide Sequence RTQTTSAKQEKAP , is from C Terminus
Human Gene ID(s) 5393
Non-Human GeneID(s)
Important Comments This antibody is expected to recognize both reported isoforms (NP_001029366.1; NP_005024.2).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB
Tested Species Human
Peptide ELISA antibody detection limit dilution 1 to 64000.
Western Blot Approx. 75kDa band observed in lysates of cell line Jurkat (calculated MW of 50.8kDa according to NP_001029366.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Alderuccio, J Exp Med.
Reference(s) Schilders G, Raijmakers R, Malmegrim KC, Vande Walle L, Saelens X, Vree Egberts W, van Venrooij WJ, Vandenabeele P, Pruijn GJ. Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis. Arthritis Res Ther. 2007;9(1)

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED