Goat anti-SUR1 / ABCC8 Antibody

Item#:

dAP-1554

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-SUR1 / ABCC8 Antibody
Principle Name	SUR1 / ABCC8
Official Symbol	ABCC8
All Name and Symbols	ABCC8; SUR1; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; ABC36; HHF1; HI; HRINS; MRP8; PHHI; SUR; TNDM2; ATP-binding cassette, sub-family C, member 8; sulfonylurea receptor (hyperinsulinemia)
Accession Number(s)	NP_000343.2
Peptide Sequence	EFDKPEKLLSRKD, is from C Terminus
Human Gene ID(s)	6833
Non-Human GeneID(s)	20927 (mouse); 25559 (rat);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 8000.
Western Blot	Approx 170kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177kDa according to NP_000343.2). Recommended concentration
Reference(s)	de Wet H, Rees MG, Shimomura K, Aittoniemi J, Patch AM, Flanagan SE, Ellard S, Hattersley AT, Sansom MS, Ashcroft FM. Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48)