Goat anti-TRPC4 Antibody |
| Principle Name | TRPC4 |
| Official Symbol | TRPC4 |
| All Name and Symbols | TRPC4; transient receptor potential cation channel, subfamily C, member 4; HTRP4; MGC119570; MGC119571; MGC119572; MGC119573; TRP4; transient receptor potential 4 |
| Accession Number(s) | NP_057263.1; NP_003297.1; NP_001129427.1; NP_001129429.1; NP_001129428.1; NP_001129430.1 |
| Peptide Sequence | KHAKEEDSSIDYD, is from internal region (near C Terminus) |
| Human Gene ID(s) | 7223 |
| Non-Human GeneID(s) | 22066 (mouse); 84494 (rat); |
| Important Comments | This antibody is expected to recognise all six reported isoforms (NP_057263.1; NP_003297.1; NP_001129427.1; NP_001129429.1; NP_001129428.1; NP_001129430.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human, Rat |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx. 110kDa band observed in Rat Brain lysates (calculated MW of 112kDa according to Human NP_057263.1 and to Rat NP_536321.1). Recommended concentration |
| Immunohistochemistry | Paraffin embedded Human Placenta and Kidney. Recommended concentration |
| Reference(s) | Song X, Zhao Y, Narcisse L, Duffy H, Kress Y, Lee S, Brosnan CF. Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture. Glia. 2005 Feb;49(3) |